Updated 7 Sep 2026

Contagion is a legendary major card out of the Synergy pool. A Venomed enemy's death spreads its Venom to nearby enemies.

Death becomes your delivery system — one Venomed kill infects the neighbors and packs unravel on their own. The heavier your stacks, the nastier the spread. Core poison clear; less relevant against lone bosses.

You can take it once · any ability can be offered it.

It pushes your build toward Poison.

What it changes

1 change
What it touchesBy how muchKind
Payoffunlocks Contagionpayoff

What has to be true first

checked before you are ever shown it
Your ability must dopoison

Cards it hangs off

1 prerequisite
Take these first

Abilities it can turn up for

all of them
Any of them — nothing on this card narrows the draft.

Plays with

what to build around it
AffinitiesPoison